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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
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2-Year Outcomes After Transcatheter Mitral Valve Replacement.
Ander Regueiro1, Jian Ye2, Neil Fam3
1Department of Cardiology, Quebec Heart & Lung Institute, Laval University, Quebec City, Canada.
JACC. Cardiovascular Interventions
|August 26, 2017
Summary
Transcatheter mitral valve replacement (TMVR) with the FORTIS valve showed feasibility and maintained mitral regurgitation reduction at 2 years. No late device-related issues were observed in this study of severe mitral regurgitation patients.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Devices
Background:
- Severe native mitral regurgitation (MR) poses significant clinical challenges.
- Limited data exist on long-term outcomes of transcatheter mitral valve replacement (TMVR) for severe MR.
Purpose of the Study:
- To evaluate the 2-year clinical and echocardiographic outcomes of TMVR using the FORTIS valve in patients with severe native MR.
- To assess the safety and efficacy of the FORTIS valve in a real-world setting.
Main Methods:
- A multicenter registry included patients with severe MR undergoing TMVR with the FORTIS valve.
- Clinical and echocardiographic data were collected at baseline, 30 days, and 1 and 2 years post-procedure.
Main Results:
- Thirteen patients with severe MR underwent TMVR; technical success was 76.9%.
- All-cause mortality was 54% at 2 years, with 2 late deaths due to heart failure.
- At 2 years, MR reduction was maintained, with no valve malfunction, significant residual MR, or left ventricular outflow tract obstruction.
Conclusions:
- Transcatheter mitral valve replacement with the FORTIS valve is feasible for severe MR.
- The reduction in mitral regurgitation was sustained at 2-year follow-up.
- No late device-related complications were observed, suggesting durability.
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