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Updated: Feb 24, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
Published on: March 17, 2023
Primary Cardiac Leiomyoma Causing Right Ventricular Obstruction and Tricuspid Regurgitation
Lucio Careddu1, Alberto Foà2, Ornella Leone3
1Pediatric Cardiac Surgery, Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum-University of Bologna, S.Orsola-Malpighi University Hospital, Bologna, Italy.
Abstract:
We report the unique case of a primary cardiac leiomyoma originating from the right ventricle and involving the tricuspid valve in a 43-year-old woman. Echocardiography showed a giant mass causing severe pulmonary stenosis and tricuspid valve regurgitation. The patient underwent surgical excision and histologic examination revealed a primary cardiac leiomyoma. To the best of our knowledge only three cases of primary cardiac leiomyoma have so far been reported, and this is the first case of primary cardiac leiomyoma involving the tricuspid valve apparatus.
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