ERS statement on protracted bacterial bronchitis in children

Ahmad Kantar1,2, Anne B Chang3,4,5,2, Mike D Shields6

  • 1Pediatric Asthma and Cough Centre, Istituti Ospedalieri Bergamaschi, University and Research Hospitals, Bergamo, Italy kantar@centropediatricotosse.com.

Insights

This European Respiratory Society statement offers a comprehensive overview of protracted bacterial bronchitis (PBB) in children, summarizing current knowledge and treatment strategies. It highlights key areas for future research to improve understanding and management of PBB.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases

Background:

  • Protracted bacterial bronchitis (PBB) is a common respiratory condition in children.
  • Current understanding of PBB's definition, pathobiology, and optimal management requires further clarification.

Purpose of the Study:

  • To provide a comprehensive overview of protracted bacterial bronchitis (PBB) in children.
  • To synthesize current knowledge on PBB definition, microbiology, pathobiology, and treatment.
  • To identify key areas for future research in PBB.

Main Methods:

  • A European Respiratory Society task force of experts was convened.
  • Systematic reviews were conducted to address key questions regarding PBB.
  • Findings were summarized, and consensus was reached on the statement content.

Main Results:

  • The statement presents the current definition, microbiology, and pathobiology of PBB.
  • Bronchoalveolar lavage findings and current treatment strategies are detailed.
  • Evidence supporting the definition of PBB is presented.

Conclusions:

  • Further research is needed to establish the disease burden and natural history of PBB.
  • A better understanding of PBB's underlying mechanisms and optimized treatment strategies are required.
  • Randomized controlled trials in primary care are essential for advancing PBB management.

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