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ERS statement on protracted bacterial bronchitis in children.

Ahmad Kantar1,2, Anne B Chang3,4,5,2, Mike D Shields6

  • 1Pediatric Asthma and Cough Centre, Istituti Ospedalieri Bergamaschi, University and Research Hospitals, Bergamo, Italy kantar@centropediatricotosse.com.

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This European Respiratory Society statement offers a comprehensive overview of protracted bacterial bronchitis (PBB) in children, summarizing current knowledge and treatment strategies. It highlights key areas for future research to improve understanding and management of PBB.

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Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases

Background:

  • Protracted bacterial bronchitis (PBB) is a common respiratory condition in children.
  • Current understanding of PBB's definition, pathobiology, and optimal management requires further clarification.

Purpose of the Study:

  • To provide a comprehensive overview of protracted bacterial bronchitis (PBB) in children.
  • To synthesize current knowledge on PBB definition, microbiology, pathobiology, and treatment.
  • To identify key areas for future research in PBB.

Main Methods:

  • A European Respiratory Society task force of experts was convened.
  • Systematic reviews were conducted to address key questions regarding PBB.
  • Findings were summarized, and consensus was reached on the statement content.

Main Results:

  • The statement presents the current definition, microbiology, and pathobiology of PBB.
  • Bronchoalveolar lavage findings and current treatment strategies are detailed.
  • Evidence supporting the definition of PBB is presented.

Conclusions:

  • Further research is needed to establish the disease burden and natural history of PBB.
  • A better understanding of PBB's underlying mechanisms and optimized treatment strategies are required.
  • Randomized controlled trials in primary care are essential for advancing PBB management.