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Updated: Jan 10, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

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Early Diagnosis of Non-Cystic Fibrosis Bronchiectasis in Childhood: Shedding Light on Barriers and Opportunities

Michele Ghezzi1, Maria Di Cicco2,3, Giulia Canali1

  • 1Department of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, Milan, Italy.

Pediatric Pulmonology
|November 25, 2025
PubMed

Insights

Early diagnosis of bronchiectasis in children is crucial. Identifying this lung condition sooner can halt disease progression and prevent structural lung damage, improving outcomes for pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine

Background:

  • Bronchiectasis is a chronic respiratory syndrome marked by persistent cough, mucus, and bronchial dilation.
  • Diagnosis typically relies on high-resolution chest tomography.
  • Childhood bronchiectasis is often underdiagnosed, despite the long progression from initial bronchitis.

Purpose of the Study:

  • To analyze barriers to timely diagnosis of non-cystic fibrosis bronchiectasis in children.
  • To explore novel strategies for enhancing diagnostic algorithms and patient care.

Main Methods:

  • Review of diagnostic challenges in pediatric bronchiectasis.
  • Discussion of potential improvements in diagnostic approaches.

Main Results:

  • Significant barriers exist for the early detection of bronchiectasis in pediatric populations.
  • New diagnostic avenues and patient management opportunities are identified.

Conclusions:

  • Prompt diagnosis in children is essential to interrupt the infection-inflammation cycle.
  • Early intervention can reverse or halt disease progression and lung injury.
  • Further research is needed for pediatric to adult care transition programs.
Abstract

Keywords:
chest computed tomographychildrenchronic coughnon‐CF bronchiectasisrecurrent respiratory infections

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