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Updated: Feb 24, 2026

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Performing the Parryscope technique gently for office tubal patency assessment
J Preston Parry1, Daniel Riche2, John Rushing3
1Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Mississippi Medical Center, Jackson, Mississippi.
Objective:
To demonstrate a novel approach to office tubal patency assessment through infusing air into saline during flexible office hysteroscopy. We also provide data addressing pain and patient experience relative to hysterosalpingography (HSG).
Design:
Video presentation of clinical technique with supportive crossover data (Canadian Task Force classification II-1). Its University of Mississippi Medical Center Institutional Review Board protocol number is 2013-0230.
Setting:
Academic hospital.
Patient(S):
Women undergoing office hysteroscopy and ultrasound, with a subset also having HSG.
Intervention(S):
Air infusion into saline during office hysteroscopy.
Main Outcome Measure(S):
The focus is on demonstrating how the technique appears and is performed, with supplemental Likert data addressing subjective pain and preference relative to HSG.
Result(S):
When performed as described, this office technique has 98.3%-100% sensitivity to tubal occlusion and 83.7% specificity. The gentle technique is central to accurate outcomes, which is facilitated through use of a small-caliber (<3 mm), flexible hysteroscope and avoiding uterine overdistention. Patients are far more likely to report maximum discomfort with HSG. Among patients who also had HSG, 92% somewhat or strongly prefer hysteroscopic assessment. Also, 96% of patients reporting maximum discomfort with HSG had mild to no discomfort with the described technique.
Conclusion(S):
Air-infused saline at flexible office hysteroscopy can accurately, gently, and rapidly assess tubal patency. Coupled with strong patient preference for this technique over HSG, it is a promising option for evaluating fertility.
Clinical Trail Registration Number:
NCT02005263.
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