Extra pelvic endometriosis: Retrospective analysis on 200 cases in two different countries
Michail Matalliotakis1, George N Goulielmos2, Ioannis Kalogiannidis3
1Department of Obstetrics & Gynecology, Venizeleio General Hospital of Heraklion, Crete, Greece; Section of Molecular Pathology and Human Genetics, Department of Internal Medicine, School of Medicine, University of Crete, Heraklion, Greece.
Summary
Extrapelvic endometriosis most commonly affects the gastrointestinal and urinary systems, with a higher incidence on the left side. Patient characteristics and reproductive history did not differ significantly between pelvic and extrapelvic endometriosis cases.
Area of Science:
- Gynecology
- Surgical Pathology
Background:
- Endometriosis is a condition where tissue similar to the lining inside the uterus appears outside the uterus.
- Extrapelvic endometriosis, occurring outside the pelvic cavity, is less common but can affect various organs.
Purpose of the Study:
- To investigate the patient characteristics and common locations of extrapelvic endometriosis.
- To compare demographic and reproductive factors between patients with pelvic and extrapelvic endometriosis.
Main Methods:
- A retrospective review of 1000 women with endometriosis over 20 years identified 200 cases of extrapelvic endometriosis.
- Data collected included patient demographics, symptoms, surgical history, diagnostic methods, histopathology, and location of implants.
- Statistical analysis used chi-squared and Mann-Whitney U tests to compare incidences.
Main Results:
- The gastrointestinal tract (52%) and urinary system (35%) were the most frequent sites of extrapelvic endometriosis.
- Left-sided ureter involvement (24.5%) was significantly higher than right-sided ureter involvement (10.5%).
- No significant differences were found in age, weight, symptoms, menarche, endometriosis stage, parity, or family history between pelvic and extrapelvic cases.
Conclusions:
- The gastrointestinal and urinary systems are primary sites for extrapelvic endometriosis.
- Demographic, menstrual, and reproductive characteristics are similar in women with pelvic and extrapelvic endometriosis.


