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Published on: June 23, 2015
Comparison of MRI segmentation techniques for measuring liver cyst volumes in autosomal dominant polycystic kidney
Zerwa Farooq1, Ashkan Heshmatzadeh Behzadi1, Jon D Blumenfeld2
1Department of Radiology, Weill Cornell Medical Center, New York, NY, United States.
Purpose:
To compare MRI segmentation methods for measuring liver cyst volumes in autosomal dominant polycystic kidney disease (ADPKD).
Methods:
Liver cyst volumes in 42 ADPKD patients were measured using region growing, thresholding and cyst diameter techniques. Manual segmentation was the reference standard.
Results:
Root mean square deviation was 113, 155, and 500 for cyst diameter, thresholding and region growing respectively. Thresholding error for cyst volumes below 500ml was 550% vs 17% for cyst volumes above 500ml (p<0.001).
Conclusion:
For measuring volume of a small number of cysts, cyst diameter and manual segmentation methods are recommended. For severe disease with numerous, large hepatic cysts, thresholding is an acceptable alternative.
