Related Experiment Video
Updated: Feb 24, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
Matilde Sanchez Conde1, María Jesús Vivancos Gallego2, Santiago Moreno Guillen3
1Infectious Disease Unit, Hospital Ramón y Cajal, Madrid. Instituto Ramón y Cajal de Investigación Sanitaria (Ramón y Cajal Health Research Institute) (IRYCIS), Madrid.. msconde@gmail.com.
Abstract:
Despite the global stabilization of the number of new HIV infections in recent years, there has been an increase in new infections among men who have sex with men. This fact indicates the lack of effectiveness of the measures and prevention campaigns established so far for this group. It is therefore necessary to implement alternative preventive measures for them. Pre-exposure pharmacological prophylaxis (PrEP) is one of the best evaluated options and has had high protection rates in both clinical and real-life trials. The strategy has also shown an adequate profile in terms of safety, tolerance, adverse effects and cost-effectiveness in the studies carried out to assess this important topic.
More Related Videos
Related Concept Videos
Sexually Transmitted Infections
Retrovirus Life Cycles
Preclinical Development: Overview
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

