Dedicated paediatric Outpatient Parenteral Antimicrobial Therapy medical support: a pre-post observational study

Ariel O Mace1, Charlie McLeod2, Daniel K Yeoh2

  • 1Department of General Paediatrics, Princess Margaret Hospital for Children, Perth, Australia.

Insights

Introducing a dedicated medical team to paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT) improved patient monitoring and reduced hospital readmissions. This enhances care delivery in home-based settings.

Area of Science:

  • Pediatric infectious diseases
  • Health services research

Background:

  • Paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT) offers benefits but carries risks.
  • Evidence for mitigating these risks in home-based care is limited.

Purpose of the Study:

  • To evaluate the impact of a dedicated medical team on paediatric OPAT outcomes.
  • To define the role of enhanced medical oversight in improving patient safety and care.

Main Methods:

  • Prospective observational cohort study over 24 months.
  • Pre-post analysis of a Hospital in the Home (HiTH) programme.
  • Inclusion of all non-haematology/oncology OPAT admissions.

Main Results:

  • Improved adherence to monitoring guidelines (OR 4.90).
  • Significantly reduced hospital readmissions (OR 0.45).
  • Decreased proportion of prolonged OPAT (≥7 days) (OR 0.67).

Conclusions:

  • A dedicated medical team positively impacted paediatric OPAT outcomes.
  • Medical governance is crucial for nurse-led home-based services.
  • Findings support structured medical oversight in paediatric OPAT.
Abstract

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