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Updated: Feb 23, 2026
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Aggregation-induced accelerating peroxidase-like activity of gold nanoclusters and their applications for
Hong Liao1, Guangjuan Liu, Yun Liu
1Chongqing Key Laboratory of Green Synthesis and Applications, and Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, China. lianzhehu@cqnu.edu.cn.
Abstract:
In this study, we found that Pb2+-induced aggregation can greatly accelerate the peroxidase-like activity of Au nanoclusters (Au-NCs). The catalytic activities of Au-NCs toward peroxidase substrate 3,3',5,5'-tetramethylbenzidine (TMB) oxidation in the presence of H2O2 are nearly 10-fold increased after the Pb2+-induced aggregation. Based on this finding, a simple and reliable colorimetric method for Pb2+ detection was developed.
