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Towards Practical Endoscopic Mass Spectrometry.

Lee Chuin Chen1, Kentaro Yoshimura2, Satoshi Ninomiya1

  • 1Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi.

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|August 31, 2017
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Summary
This summary is machine-generated.

This study reviews remote mass spectrometry for in-situ and in-vivo analysis inside the body. A moving string probe enables sample collection and transport for endoscopic mass spectrometry applications.

Keywords:
ambient ionizationendoscopyin-situ and in-vivo analysismoving sampling stringremote mass spectrometry

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Area of Science:

  • Analytical Chemistry
  • Medical Technology

Background:

  • Remote mass spectrometry enables in-situ and in-vivo analysis within biological cavities.
  • Current techniques face challenges in sample collection and transport for internal analyses.

Purpose of the Study:

  • To review viable remote mass spectrometric techniques for endoscopic mass spectrometry.
  • To present a novel moving string sampling probe for remote sample collection and transport.

Main Methods:

  • Review of existing remote mass spectrometry techniques.
  • Development and testing of a moving string sampling probe for sample transfer.
  • Discussion of probe miniaturization for endoscopic integration.

Main Results:

  • Identified viable remote mass spectrometry techniques for internal body analysis.
  • Demonstrated the effectiveness of the moving string probe for sample collection and transport.
  • Highlighted the potential for integrating this method into medical endoscopes.

Conclusions:

  • Remote mass spectrometry offers promising avenues for in-situ and in-vivo diagnostics.
  • The moving string probe represents a significant advancement for endoscopic mass spectrometry.
  • Further miniaturization could enable direct integration into clinical endoscopic procedures.