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Updated: Feb 23, 2026
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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
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Advanced Percutaneous Mechanical Circulatory Support Devices for Cardiogenic Shock
P Elliott Miller1, Michael A Solomon, Dorothea McAreavey
11Critical Care Medicine, National Institutes of Health Clinical Center, Bethesda, MD. 2Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, Bethesda, MD.
Critical Care Medicine
|September 1, 2017
Summary
Temporary mechanical circulatory support devices show promise for cardiogenic shock treatment, improving hemodynamics but not yet mortality. Further research is needed to confirm benefits and address high complication rates.
Area of Science:
- Cardiology
- Critical Care Medicine
- Medical Devices
Background:
- Cardiogenic shock carries a high mortality rate despite current therapies.
- Limited treatment options existed for refractory cardiogenic shock before recent advancements.
Purpose of the Study:
- To review temporary percutaneous mechanical circulatory support (pMCS) devices for cardiogenic shock.
- To examine current evidence, contraindications, complications, and future directions of pMCS.
Main Methods:
- A comprehensive MEDLINE search was performed using relevant MeSH terms.
- Included randomized controlled trials and observational studies focusing on pMCS in cardiogenic shock.
Main Results:
- Devices like Impella, TandemHeart, and extracorporeal membrane oxygenation (ECMO) are increasingly used.
- pMCS devices improve hemodynamic support but have not yet demonstrated mortality reduction.
- Veno-arterial ECMO offers biventricular support and oxygenation but carries significant vascular complication risks.
Conclusions:
- Despite high mortality, pMCS offers potential for improved outcomes in cardiogenic shock.
- Further research and device development are crucial to overcome limitations and high complication rates.
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