Related Experiment Video
Updated: Feb 23, 2026
07:21
Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
1.1K
Comparison of Clinical Outcomes of Intracranial Aneurysms: Procedural Rupture versus Spontaneous Rupture
1From the Departments of Neurosurgery (H.H.C.), Dongguk University College of Medicine, Dongguk University Hospital, Ilsan, Korea.
AJNR. American Journal of Neuroradiology
|September 2, 2017
Summary
Procedural rupture of intracranial aneurysms during endovascular treatment had better clinical outcomes than spontaneous rupture. This suggests that even with treatment complications, patient recovery can be more favorable.
Area of Science:
- Neurosurgery
- Interventional Neurology
- Vascular Neurology
Background:
- Procedural rupture of intracranial aneurysms is a serious complication of endovascular treatment.
- Comparing outcomes of procedural vs. spontaneous rupture is crucial for risk assessment.
Purpose of the Study:
- To evaluate and compare clinical outcomes of patients experiencing procedural rupture of unruptured saccular intracranial aneurysms versus those with spontaneously ruptured aneurysms.
Main Methods:
- Retrospective review of 1340 patients with 1595 unruptured saccular intracranial aneurysms treated with endovascular coil embolization (Feb 2010-Dec 2014).
- Comparison of clinical outcomes between 19 patients with procedural rupture and 198 patients with spontaneous rupture.
Main Results:
- Procedural rupture occurred in 1.4% of patients, with 26.3% morbidity and no mortality.
- Patients with procedural rupture had smaller hemorrhage volumes and better 6-month modified Rankin Scale scores (5.3% vs. 26.8%).
- Spontaneous rupture was a significant risk factor for worse clinical outcomes (OR = 14.9).
Conclusions:
- Clinical outcomes following procedural rupture of intracranial aneurysms are more favorable than those of spontaneous rupture.
- Endovascular treatment, despite potential rupture risk, can lead to better patient prognoses compared to natural aneurysm rupture.
Related Concept Videos
01:26Aneurysm III: Interprofessional Care
365
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
365
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
406
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
406
01:30Aneurysm I: Introduction
518
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
518