Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Accessory Structures of the Eye

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The NYEE-Orbis oculoplastic surgery online curriculum: global access to oculoplastics education.

International ophthalmology·2025

Same author

Conjunctival Squamous Cell Carcinoma Presenting after Chemical Burn Injury.

Ophthalmology·2024

Same author

Sympathetic Ophthalmia in Patients with Enucleation or Evisceration: Pathology Laboratory and IRIS<sup>®</sup> Registry Experience.

Ocular oncology and pathology·2023

Same author

Tips for success when using social media for online medical education in dermatopathology.

JAAD international·2023

Same author

A Novel Video-Based Skills Curriculum for Incoming Ophthalmology Residents.

Seminars in ophthalmology·2023

Same author

Tarsoconjunctival flap for scleromalacia related to treatments for conjunctival melanoma.

American journal of ophthalmology case reports·2023

Search research articles

Related Experiment Video

Updated: Feb 23, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

Eyelid trichilemmal carcinoma.

Michael K Chai¹, Phillip Tenzel¹, Codrin Iacob¹

¹New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY 10003, United States.

Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society

|September 2, 2017

Summary

Trichilemmal carcinomas are rare eyelid tumors. Accurate diagnosis requires histopathology and immunohistochemistry to distinguish them from similar lesions like trichoepithelioma.

Keywords:

Basal cell carcinoma Eyelid Trichilemmal carcinoma Trichoepithelioma

More Related Videos

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

Published on: November 11, 2025

Related Experiment Videos

Last Updated: Feb 23, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

Published on: November 11, 2025

Area of Science:

Dermatopathology
Ophthalmology
Oncology

Background:

Trichilemmal carcinomas are rare malignant adnexal tumors.
These tumors can occur on the head and, less commonly, the eyelid.
Distinguishing trichilemmal carcinoma from basal cell carcinoma and trichoepithelioma is crucial for proper management.

Purpose of the Study:

To report a case of eyelid trichilemmal carcinoma.
To review the literature on histopathology, differential diagnosis, and management of trichilemmal carcinoma.
To aid histopathologists and clinicians in identifying and treating these challenging eyelid lesions.

Main Methods:

Histopathological analysis of an eyelid mass.
Immunohistochemical analysis for differential diagnosis.
Literature review of trichilemmal carcinoma.

Main Results:

An eyelid mass initially diagnosed as trichoepithelioma by incisional biopsy was confirmed as trichilemmal carcinoma by excisional biopsy.
Histopathological and immunohistochemical findings are key to differentiating trichilemmal carcinoma from other adnexal tumors.

Conclusions:

Accurate diagnosis of eyelid masses requires careful histopathological and immunohistochemical evaluation.
Trichilemmal carcinoma is a rare but important differential diagnosis for eyelid tumors.
This case and literature review highlight the importance of considering trichilemmal carcinoma in the differential diagnosis of eyelid lesions.