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MANOTA: a promising bifunctional chelating agent for copper-64 immunoPET

M Moreau1, S Poty, J-M Vrigneaud

  • 1Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR6302, CNRS, Université Bourgogne Franche-Comté, Dijon, France. franck.denat@u-bourgogne.fr.

Dalton Transactions (Cambridge, England : 2003)
|September 2, 2017
PubMed
Summary

New bifunctional chelating agents (BFCs) enable efficient copper-64 radiolabelling of antibody fragments for targeted cancer imaging. MANOTA demonstrated low non-specific liver uptake, making it a promising tool for developing stable, HER2-targeting imaging agents.

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