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Cerebellar abscesses, infective endocarditis and bacteraemia due to a rare pathogen: Streptococcus constellatus
1Hospital Universitario de Mostoles, Mostoles, Madrid, Spain.
Abstract:
Intracranial infections may result from contiguity, such as mastoiditis or acute otitis media, or from haematogenous dissemination from an infectious source. Streptococcus constellatus, a coccus from the normal genital, oral and gastrointestinal flora, has a tendency to form abscesses, but not to cause infective endocarditis (IE). Also, S. constellatus is an extremely rare causative agent of brain abscess. We report the case of a woman with a colorectal tumour who presented with IE and cerebellar abscesses due to a S. constellatus bacteraemia.
Insights
Streptococcus constellatus, typically a normal flora, rarely caused infective endocarditis and cerebellar abscesses in a patient with colorectal cancer. This case highlights an unusual presentation of S. constellatus bacteraemia.
Area of Science:
- Infectious Diseases
- Neurology
- Cardiology
Background:
- Intracranial infections arise from contiguous spread or hematogenous dissemination.
- Streptococcus constellatus, a commensal bacterium, typically causes localized infections and rarely infective endocarditis (IE) or brain abscesses.
Observation:
- A patient with a colorectal tumor developed IE and cerebellar abscesses.
- Blood cultures identified Streptococcus constellatus as the causative agent of bacteraemia.
Findings:
- This case demonstrates an exceptionally rare instance of S. constellatus causing both IE and brain abscesses.
- The patient's colorectal tumor may have served as the primary source for the S. constellatus bacteraemia.
Implications:
- Highlights the potential for S. constellatus to cause severe systemic infections, including IE and brain abscesses.
- Suggests a need for heightened awareness of S. constellatus in patients with unexplained bacteraemia, particularly those with underlying conditions like malignancy.
- Underscores the importance of considering unusual pathogens in the differential diagnosis of brain abscesses and endocarditis.
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