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Wells' Syndrome Successfully Treated with Colchicine.
Álvaro Iglesias Puzas1, Laura Mesa Álvarez1, Ángeles Flórez Menéndez1
1Dermatology Department, Complejo Hospitalario Universitario de Pontevedra, EOXI Pontevedra-Salnés, Pontevedra, Spain.
Case Reports in Dermatology
|September 5, 2017
Summary
Colchicine offers a safe and effective treatment for Wells' syndrome (eosinophilic cellulitis), a chronic skin condition. This approach provides significant clinical improvement with no side effects, benefiting patients with recurrent episodes.
Area of Science:
- Dermatology
- Rheumatology
Background:
- Eosinophilic cellulitis, or Wells' syndrome, is a rare, chronic inflammatory skin disorder with unknown causes.
- Corticosteroids are the primary treatment but have drawbacks, including ineffectiveness in some patients and frequent relapses.
Observation:
- A patient with a 24-year history of symptomatic, generalized Wells' syndrome was treated.
- The patient received colchicine at a dosage of 1 mg daily.
Findings:
- Colchicine treatment resulted in substantial clinical improvement in the patient's skin lesions.
- No adverse side effects were observed during the treatment period.
Implications:
- Colchicine presents a promising, safe alternative for managing Wells' syndrome, especially for patients needing long-term treatment.
- This case suggests colchicine should be considered as a viable therapeutic option for eosinophilic cellulitis, particularly in recurrent or steroid-resistant cases.
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