Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

H2-receptor antagonists: development and application.

New England and Regional Allergy Proceedings

|July 1, 1986

Summary

This summary is machine-generated.

H2-receptor antagonists like ranitidine and cimetidine effectively treat peptic ulcers. Ranitidine offers greater potency and fewer side effects, guiding future therapeutic trends toward optimized acid control.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Immunogenicity of hepatitis B vaccine in healthy very low birth weight infants.

The Journal of pediatrics·1997

Same author

Anaesthesia and the Research Assessment Exercise.

Anaesthesia·1997

Same author

Depressed autoantibody synthesis in Trypanosoma cruzi-infected rats born to mothers undergoing this infection during pregnancy.

Journal of reproductive immunology·1997

Same author

Neuromuscular block.

Anaesthesia and intensive care·1997

Same author

The role of private-for-profit managed behavioral health in the public sector.

Administration and policy in mental health·1997

Same author

Effect of glucocorticoids on the adrenocortical axis responses to electrical stimulation of the amygdala and the ventral noradrenergic bundle.

Brain research·1997

Same journal

Official abstracts of papers o the XIII International Congress of Allergology and Clinical Immunology (ICACI). October 16-21, 1988, Montreux, Switzerland.

New England and regional allergy proceedings·1988

Same journal

A new look at conifer allergy.

New England and regional allergy proceedings·1988

Same journal

Eastern pine sensitivity in New England.

New England and regional allergy proceedings·1988

Same journal

Mountain cedar pollinosis: can it occur in non-atopics?

New England and regional allergy proceedings·1988

Same journal

The management of patients with sulfonamide allergy.

New England and regional allergy proceedings·1988

Same journal

Exercise-induced anaphylaxis.

New England and regional allergy proceedings·1988

See all related articles

Area of Science:

Gastroenterology
Pharmacology

Background:

Peptic ulcer disease treatment has been revolutionized by H2-receptor antagonists.
Ranitidine and cimetidine are established treatments for healing and preventing ulcer relapse.

Purpose of the Study:

To review the efficacy and safety of H2-receptor antagonists in peptic ulcer disease.
To compare ranitidine and cimetidine, highlighting their pharmacological differences.
To discuss current therapeutic trends and potential new applications for H2-receptor antagonists.

Main Methods:

Review of existing literature on H2-receptor antagonists.
Comparative analysis of ranitidine and cimetidine based on chemical structure and clinical data.

Main Results:

Related Experiment Videos

Both ranitidine and cimetidine demonstrate safety and effectiveness in healing gastric and duodenal ulcers.
Ranitidine exhibits superior potency, longer duration of action, and a better side effect profile compared to cimetidine.
Therapeutic strategies are shifting towards less frequent dosing and nocturnal acid suppression.

Conclusions:

H2-receptor antagonists are crucial in managing peptic ulcer disease.
Ranitidine presents advantages over cimetidine for patient treatment.
Future research may uncover additional therapeutic uses for this drug class.