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Polymer/Amorphous Salt Solid Dispersions of Ciprofloxacin.

Hanah Mesallati1, Lidia Tajber2

  • 1Synthesis and Solid State Pharmaceutical Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, College Green, Dublin 2, Ireland.

Pharmaceutical Research
|September 7, 2017
PubMed
Summary

Formulating amorphous ciprofloxacin succinate salts into polymer solid dispersions enhanced their stability. However, this approach did not significantly improve drug solubility or permeability compared to amorphous salts.

Keywords:
Ciprofloxacinamorphous salt solid dispersionpermeabilitysolubilitystability

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