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Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Splenic and Kidney Infarct: Sequelae of Subacute Streptococcus mitis Bacterial Endocarditis
Sushilkumar Satish Gupta1, Rajeswer Sarasam1, Siddharth Wartak2
1Department of Medicine and Cardiology, Maimonides Medical Center, Brooklyn, NY, USA.
Abstract:
Infective endocarditis (IE) is caused due to the vegetation on the heart valves, myocardium wall, or the pacemaker leads. Vegetation is a lesion that appears as a consequence of successive deposition of platelets and fibrin on the endothelial surface of the heart. Colonies of microbes can be usually found under the vegetation. Heart valves are involved more frequently as compared to other places. Streptococcus mitis, formerly known as S. mitior, is a commensal of the oral flora, however, if there of loss of integrity of the mucous membrane, the infection may disseminate to the blood flow. We describe here a rare presentation of S. mitis, causing IE and its complications in an immunocompetent patient.
Insights
This study reports a rare case of infective endocarditis caused by Streptococcus mitis in an immunocompetent patient. It highlights the potential for oral bacteria to lead to serious heart valve infections and complications.
Area of Science:
- Cardiology
- Infectious Diseases
- Microbiology
Background:
- Infective endocarditis (IE) involves heart valve or cardiac device vegetation, often microbial.
- Vegetation forms from platelet and fibrin deposition on the endocardium, harboring microbial colonies.
- Heart valves are the most common site for IE development.
Observation:
- Streptococcus mitis, an oral commensal, can cause IE when mucous membranes are compromised.
- This case details a rare presentation of S. mitis-induced IE.
- The patient was immunocompetent, making the infection unusual.
Findings:
- S. mitis was identified as the causative agent of infective endocarditis.
- The infection led to significant complications in the patient.
- The case underscores the pathogenicity of S. mitis in specific circumstances.
Implications:
- Highlights the importance of considering oral flora in IE etiology, even in immunocompetent individuals.
- Suggests potential for S. mitis to cause severe cardiovascular complications.
- Emphasizes the need for vigilance in managing oral health to prevent systemic infections.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis I: Introduction
Rheumatic Heart Disease I: Introduction
Mitral Stenosis I: Introduction
Myocarditis I: Introduction
Endocarditis III: Medical Management

