Cyclodextrin-Catalyzed Organic Synthesis: Reactions, Mechanisms, and Applications
Chang Cai Bai1, Bing Ren Tian2, Tian Zhao3
1School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China. changcaibai@163.com.
Abstract:
Cyclodextrins are well-known macrocyclic oligosaccharides that consist of α-(1,4) linked glucose units and have been widely used as artificial enzymes, chiral separators, chemical sensors, and drug excipients, owing to their hydrophobic and chiral interiors. Due to their remarkable inclusion capabilities with small organic molecules, more recent interests focus on organic reactions catalyzed by cyclodextrins. This contribution outlines the current progress in cyclodextrin-catalyzed organic reactions. Particular emphases are given to the organic reaction mechanisms and their applications. In the end, the future directions of research in this field are proposed.
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