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Updated: Feb 23, 2026

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
New sepsis criteria: do they replace or complement what is known in the approach to the infectious patient?
J González Del Castillo1, C Clemente, F J Candel
1Juan González del Castillo, Emergency Department. Hospital Universitario Clínico San Carlos. Calle Profesor Martín-Lagos s/n, 28040 Madrid, Spain. jgonzalezcast@gmail.com.
Abstract:
There have recently been profound changes in both the definitions of sepsis and septic shock and the diagnostic criteria established for daily clinical practice. In addition, a new screening tool known as qSOFA has been introduced to identify patients at risk of a poor short-term outcome. This score has been accompanied by some controversy due to presenting a lower sensitivity than the systemic inflammatory response criteria previously used to identify such patients. In this article, we shall summarise and analyse the most important recently published studies in relation to these new criteria.
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