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Measuring oral contraceptive adherence using self-report versus pharmacy claims data
Hallie N Nelson1, Sonya Borrero2, Erik Lehman3
1Penn State College of Medicine.
Contraception
|September 9, 2017
Summary
Proportion of Days Covered (PDC) and self-report measures of oral contraceptive pill (OCP) adherence show varying results. Younger women and those not in relationships were less adherent, highlighting the need for tailored adherence strategies.
Area of Science:
- Reproductive Health
- Pharmaceutical Sciences
- Health Services Research
Background:
- Medication adherence is crucial for oral contraceptive pill (OCP) efficacy.
- Proportion of Days Covered (PDC) using claims data is a potential objective measure of adherence.
- Self-report is a common but potentially less accurate method for assessing adherence.
Purpose of the Study:
- To compare Proportion of Days Covered (PDC) with self-report for measuring OCP adherence.
- To identify individual-level factors associated with OCP adherence.
Main Methods:
- A study involving 384 OCP users compared self-report and PDC adherence over 3 months.
- Multivariable logistic regression models were used to identify predictors of adherence.
Main Results:
- High adherence rates varied: 76% by self-report, 68% by PDC, and 54% by both.
- Younger women (18-33 years) and unpartnered women showed lower adherence.
- Relationship status, Protestant religion, and higher contraceptive self-efficacy predicted higher adherence.
Conclusions:
- PDC, alone or combined with self-report, may offer a valuable alternative for measuring OCP adherence.
- Further validation of PDC as an adherence measurement tool is recommended.
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