RADAR Dose Estimate Report: A Compendium of Radiopharmaceutical Dose Estimates Based on OLINDA/EXM Version 2.0

Area of Science:

• Nuclear Medicine
• Radiological Physics
• Medical Imaging

Background:

• Radiation dose estimation is crucial for nuclear medicine and molecular imaging.
• Previous dose estimates relied on older computational models.
• Accurate biokinetic data are essential for reliable dose calculations.

Purpose of the Study:

• To present an updated compendium of radiation dose estimates for approximately 100 radiopharmaceuticals.
• To incorporate a new generation of realistic, voxel-based human computational phantoms.
• To utilize the most recent biokinetic models for improved accuracy.

Main Methods:

• Utilized the OLINDA/EXM version 2.0 software for dose calculations.
• Employed voxel-based computational phantoms from the RADAR committee (Society of Nuclear Medicine and Molecular Imaging).
• Incorporated International Commission on Radiological Protection (ICRP) 2007 recommendations and recent biokinetic models.

Main Results:

• Developed dose estimates for about 100 radiopharmaceuticals.
• The estimates are based on realistic, modern computational phantoms and updated biokinetic data.
• The compendium is presented in an electronic format.

Conclusions:

• The updated compendium provides a valuable resource for nuclear medicine professionals.
• The electronic format allows for future modifications and additions of new radiopharmaceuticals.
• This work enhances the accuracy of radiation dose assessments in molecular imaging.