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Updated: Feb 23, 2026
Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy
Published on: March 5, 2021
Platinum-coated Core-Shell Gold Nanorods as Multifunctional Orientation Sensors in Differential Interference Contrast
1Advanced Nano Bio Imaging and Spectroscopy (ANBIS) Laboratory, Department of Chemistry, University of Ulsan.
Abstract:
We characterized the optical properties of single platinum-coated core-shell gold nanorods (Pt-AuNRs) under dark-field (DF) and differential interference contrast (DIC) microscopy. Furthermore, we examined their potential use as multifunctional orientation probes. Longitudinal surface plasmon resonance damping was observed for single Pt-AuNRs due to Pt metals coated on the AuNR surface under single-particle scattering spectroscopy. Despite the strong plasmon damping with a much-decreased scattering intensity, DIC microscopy allowed us to detect single Pt-AuNRs with much higher sensitivity. We found polarization-dependent DIC images and intensities of single Pt-AuNRs, which allowed us to determine their orientation angle under DIC microscopy. Therefore, we report that single Pt-AuNRs can be used to develop multifunctional orientation probes under DIC microscopy.
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