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Updated: Feb 23, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Primary percutaneous coronary intervention for inferior ST-segment elevation myocardial infarction in a patient
Roberto Spina1, Maithri Siriwardena2, Nicole Bart3
1Department of Interventional Cardiology, St Vincent's Hospital, Sydney, New South Wales, Australia.
Insights
This case study details a patient with a HeartWare left ventricular assist device (LVAD) who experienced a heart attack and ventricular tachycardia. Successful percutaneous coronary intervention (PCI) resolved these critical issues, offering new insights for high-risk cardiac patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Mechanical Circulatory Support
Background:
- A 63-year-old male with ischemic cardiomyopathy and a HeartWare left ventricular assist device (LVAD) presented with ventricular tachycardia and inferior ST-elevation myocardial infarction (STEMI).
- The patient also exhibited acute right ventricular (RV) dysfunction secondary to the STEMI.
Observation:
- The patient underwent primary percutaneous coronary intervention (PCI) with balloon angioplasty and stent placement in the right coronary artery.
- Following PCI, the patient's ventricular arrhythmias resolved, RV systolic dysfunction improved, and RV size normalized.
Findings:
- This is the first reported case of primary PCI in a patient with an established LVAD.
- PCI in patients on full mechanical circulatory support is uncommon but feasible.
Implications:
- This case highlights the potential for emergent revascularization in LVAD patients experiencing acute coronary syndrome.
- It raises important clinical considerations for managing high-risk cardiac patients requiring mechanical support and emergent PCI.
Abstract:
A 63-year-old man with an ischaemic cardiomyopathy, supported by the HeartWare left ventricular assist device (LVAD), presented with ventricular tachycardia and inferior ST-elevation myocardial infarction (STEMI) with associated acute right ventricular (RV) dysfunction. He underwent primary percutaneous coronary intervention with balloon angioplasty and placement of three drug-eluting stents in the proximal-to-mid right coronary artery. Post-procedure, ventricular arrhythmias abated, RV systolic dysfunction resolved and RV size normalised. Percutaneous coronary intervention (PCI) facilitated by the use of miniaturised percutaneous LVAD has become an increasingly available treatment option for high-risk patients. PCI in patients on established full mechanical circulatory support is not a common occurrence. Indeed, to our knowledge, this is the first case of primary percutaneous coronary intervention on an LVAD-supported heart reported in the medical literature. The case raises several specific issues that are of peculiar interest to clinicians involved in the care of patients supported by mechanical assist devices who experience an acute coronary syndrome requiring emergent revascularisation.
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