Blood volume recovery in hemorrhaged Japanese quail

1. Blood volume and plasma biochemical changes and feed and water consumption in response to a hemorrhage by phlebotomy of 30% of the calculated total blood volume with and without replacement of blood volume with physiological saline were determined in juvenile male Coturnix coturnix japonica. 2. Plasma protein and osmolality decreased rapidly posthemorrhage and did not recover by 72 hr posthemorrhage. 3. Plasma glucose, Na+ and K+ increased within 1 hr postphlebotomy. Plasma Na+ returned to nonphlebotomized levels within 6 hr postphlebotomy. 4. Saline replacement of blood volume resulted in hypervolemia within 3-5 min postphlebotomy. 5. Phlebotomized quail receiving no saline recovered blood volume to 0 hr (nonphlebotomized) levels within 1 hr postphlebotomy.