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Updated: Feb 23, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
Atopic dermatitis: pathogenesis
Emma Guttman-Yassky1, Andrea Waldman2,3, Jusleen Ahluwalia2,3
1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, New York, USA. eguttman@mail.rockefeller.edu.
Abstract:
Atopic Dermatitis (AD) is a complex inflammatory cutaneous disorder characterized by immune mediated inflammation and epidermal barrier dysfunction. Arising from a complex interplay between environmental and genetic factors, the definitive etiology of AD is perplexing and controversial. Advances in molecular medicine are radically transforming our understanding of AD pathogenesis. Increasing knowledge on the pathogenesis of AD results in novel therapeutic targets and pathways. This article details the pathogenesis section of the Curriculum United for Better Eczema Care (CUBE-C), facilitating primary care and sub-specialist education on the scientific advances driving recent AD therapeutic innovations.
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