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Updated: Feb 23, 2026

Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
Published on: February 2, 2024
[Morbimortality associated to nutritional status and feeding path in children with cerebral palsy]
M J Figueroa1, C Rojas2, S Barja3
1Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile.
Insights
Children with cerebral palsy (CP) and nutritional risk (NR) showed similar hospitalization and mortality rates. However, gastrostomy-fed children with CP faced higher risks than orally fed peers.
Area of Science:
- Pediatrics
- Neurology
- Nutrition Science
Background:
- Children and adolescents with cerebral palsy (CP) often experience malnutrition, impacting prognosis.
- New growth curves (Brooks, 2011) aid in nutritional assessment, with Weight/Age index cut-offs linked to morbidity and mortality.
- Nutritional status is a critical factor in managing CP complications.
Purpose of the Study:
- To assess the risk of hospitalization and death in pediatric CP patients based on their nutritional risk (NR).
- To identify specific feeding methods associated with adverse outcomes in CP.
- To inform nutritional management strategies for improved CP patient outcomes.
Main Methods:
- An observational, prospective cohort study was conducted with CP patients at an outpatient referral center.
- Demographic, socioeconomic, and nutritional assessment data were collected.
- Hospitalizations and mortality were tracked over a one-year follow-up period.
Main Results:
- The study included 81 CP patients (mean age 131.6 months, 60% male), with 77.5% lacking independent mobility.
- Twenty-three patients (28.4%) were identified with nutritional risk (NR), exhibiting lower muscle and fat mass.
- While NR did not increase hospitalization/mortality risk, gastrostomy-fed children showed significantly higher risks (RR: 2.98).
Conclusions:
- Children and adolescents with severe CP and nutritional risk had comparable morbidity and mortality to those with adequate nutritional status over one year.
- Gastrostomy feeding in CP patients was associated with significantly higher hospitalization and mortality risks compared to oral feeding.
- Nutritional assessment and feeding method are crucial considerations for managing CP patients.
Introduction:
Children and adolescents with cerebral palsy (CP) have a high prevalence of malnutrition associated to poor prognosis. For an adequate nutritional assessment, new growth curves (Brooks, 2011) are available, in which precise cut-off points in Weight/Age index correlate to increased morbidity and mortality rate.
Objective:
To evaluate risk of hospitalization and death in patients with CP, according to nutritional risk (NR).
Patients And Method:
Observational and prospective cohort study of patients with CP in an outpatient referral center. We registered demographic, socioeconomic data and nutritional assessment. During a one-year follow-up, hospitalizations and mortality were recorded. The correspondent committee extended an ethical approval.
Results:
81 CP patients were recruit, age 131.6 ± 60.4 months (25-313), 60 % male, 77.5 % without independent mobility. The 23 NR patients (28.4%) had lower muscle and fat mass (p = 0.000). During the follow-up, 29/81 patients required hospitalization (35.8%) and 4/81 died (4.9%). There was not an increased risk of hospitalization and/or mortality in NR group, but both were significantly higher in gastrostomy-fed children (RR: 2,98 CI 95%: 1.32-6.75 combining both variables).
Conclusions:
In this study, children and adolescents with severe CP and nutritional risk had similar morbidity and mortality during a one-year follow-up, compared to those with acceptable nutritional status. Both risks were higher in gastrostomy-fed than the orally fed children.
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