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Rhabdoid Meningioma of Brain - A Rare Aggressive Tumor
Sajeeb Mondal1, Rajashree Pradhan1, Subrata Pal1
1Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
Abstract:
Rhabdoid meningioma is a rare aggressive variant of meningioma, regarded as WHO Grade III type. Histologically and cytologically, it is distinctive type having abundant eosinophilic cytoplasm, cytoplasmic inclusion with eccentrically placed vesicular nuclei and prominent nucleoli. High recurrence rate and poor outcome are important features. Here, we are presenting a rare case of rhabdoid meningioma found in a recurrent meningioma of the posterior fossa in a middle-aged female. We emphasized the squash cytology and histology finding of the rare neoplasm.
Insights
Rhabdoid meningioma, a rare WHO Grade III tumor, presents aggressive features. This case highlights its distinct cytology and histology in a recurrent posterior fossa meningioma.
Area of Science:
- Neuro-oncology
- Pathology
- Cytology
Background:
- Rhabdoid meningioma is a rare, aggressive WHO Grade III variant of meningioma.
- It is characterized by distinct histological and cytological features, including abundant eosinophilic cytoplasm and cytoplasmic inclusions.
Observation:
- A rare case of rhabdoid meningioma is presented in a middle-aged female with recurrent meningioma.
- The tumor was located in the posterior fossa.
Findings:
- Squash cytology revealed characteristic rhabdoid features.
- Histological examination confirmed the diagnosis of rhabdoid meningioma, noting its aggressive nature.
Implications:
- This case underscores the importance of recognizing rhabdoid meningioma, especially in recurrent cases.
- Accurate cytological and histological diagnosis is crucial for managing this aggressive neoplasm and predicting patient outcomes.
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