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Related Concept Videos

Vaccinations01:51

Vaccinations

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Overview
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Healthcare Associated Infections II: Preventive Measures01:22

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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FDA Approved Drugs: Changes to Approved Drugs01:26

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Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...
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Immunodeficiency Diseases01:25

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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Antigens Involved in Adaptive Immunity01:26

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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
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Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
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Update From the Advisory Committee on Immunization Practices.

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The Advisory Committee on Immunization Practices (ACIP) reviews vaccine data to inform public health recommendations. They discussed key topics including infant hepatitis B vaccination and new vaccines for diseases like Zika and Dengue.

Keywords:
Advisory Committee on Immunization PracticesCenters for Disease Control and Preventionimmunization

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Area of Science:

  • Public Health
  • Immunization Practices
  • Vaccinology

Background:

  • The Advisory Committee on Immunization Practices (ACIP) is a federal advisory committee composed of medical and public health experts.
  • ACIP convenes three times annually to formulate vaccine use recommendations in the United States.
  • Members and CDC staff analyze vaccine-preventable disease epidemiology, research, safety, and efficacy data.

Purpose of the Study:

  • To present discussions and proposed recommendations from the February 2017 ACIP meeting.
  • To highlight key topics addressed, including specific vaccine recommendations and epidemiological updates.

Main Methods:

  • Review of meeting proceedings and presented data from the ACIP February 22-23, 2017 session.
  • Discussion of epidemiological trends, vaccine effectiveness, safety data, and cost analyses.

Main Results:

  • Proposed recommendations for vaccinating infants born to HBsAg-positive mothers were discussed.
  • Evaluations of influenza vaccine effectiveness, herpes zoster vaccine, and meningococcal serogroup B booster doses were presented.
  • Updates on mumps, Dengue virus, Zika virus, adult immunization, and yellow fever vaccines were provided.

Conclusions:

  • The ACIP actively reviews comprehensive data to guide vaccine recommendations for the US population.
  • The committee addresses a wide range of vaccine-preventable diseases and emerging public health concerns.
  • Discussions inform evidence-based strategies for disease prevention and control through vaccination.