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Updated: Feb 22, 2026

Metabolomic Analysis of Barley by Gas Chromatography/Mass Spectrometry
08:15

Metabolomic Analysis of Barley by Gas Chromatography/Mass Spectrometry

Published on: November 8, 2024

995

Bioactive phytochemicals in barley.

Emmanuel Idehen1, Yao Tang1, Shengmin Sang1

  • 1Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, NC, USA.

Journal of Food and Drug Analysis
|September 16, 2017
PubMed
Summary
This summary is machine-generated.

Whole grain barley consumption offers health benefits beyond fiber. Its rich phytochemicals, including antioxidants, may combat chronic diseases like cancer and diabetes.

Keywords:
barleydisease preventionfiberphytochemicalswhole grain

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Area of Science:

  • Nutritional Science
  • Biochemistry

Background:

  • Epidemiological studies link whole grain barley consumption to reduced chronic disease risk.
  • Barley's health benefits were primarily attributed to its fiber, particularly beta-glucan.
  • Emerging evidence suggests barley's phytochemicals also contribute significantly to its health-promoting properties.

Purpose of the Study:

  • To review the phytochemical composition of whole grain barley.
  • To explore the potential health benefits of barley phytochemicals in preventing nutrition-related diseases.
  • To highlight the role of phytochemicals in barley's disease-preventive effects.

Main Methods:

  • Literature review of epidemiological studies and biochemical analyses.
  • Examination of phytochemical profiles in whole grain barley.
  • Analysis of in vitro and in vivo studies on barley phytochemicals and disease models.

Main Results:

  • Whole grain barley is rich in diverse phytochemicals: phenolic acids, flavonoids, lignans, tocols, phytosterols, and folate.
  • These phytochemicals possess significant antioxidant, antiproliferative, and cholesterol-lowering activities.
  • The combined action of fiber and phytochemicals likely underlies barley's protective effects against chronic diseases.

Conclusions:

  • Barley phytochemicals play a crucial role in the health benefits associated with whole grain barley consumption.
  • These compounds show promise in mitigating risks for cancer, cardiovascular disease, diabetes, and obesity.
  • Further research into barley phytochemicals can inform dietary strategies for disease prevention.