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Updated: Feb 22, 2026

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Published on: June 13, 2025
Living systematic reviews: 2. Combining human and machine effort.
James Thomas1, Anna Noel-Storr2, Iain Marshall3
1EPPI-Centre, Department of Social Science, University College London, 18 Woburn Square, London, WC1H 0NR, UK.
New methods combining human effort and machine automation improve living systematic reviews. This hybrid approach enhances efficiency and sustainability for evidence synthesis, making reviews more feasible.
Area of Science:
- Evidence synthesis methodologies
- Health informatics
- Systematic review processes
Background:
- Living systematic reviews require sustainable and feasible approaches.
- Traditional systematic reviews face challenges in keeping pace with new research.
- Integrating human intelligence with machine automation offers potential solutions.
Purpose of the Study:
- To explore new approaches for evidence synthesis using human-machine collaboration.
- To enhance the feasibility and sustainability of living systematic reviews.
- To identify current applications and future research needs for human-machine technologies in systematic reviewing.
Main Methods:
- Developing workflows where human effort and machine automation mutually reinforce each other.
- Leveraging contributions from online communities (crowdsourcing) and traditional experts.
- Utilizing automation for tasks like searching, eligibility screening, data extraction, and risk of bias assessment.
Main Results:
- Human-machine collaboration can significantly enhance systematic review productivity.
- Automation assists in various systematic review tasks, freeing up human resources for complex judgments.
- New workflows demonstrate potential for more effective and efficient evidence synthesis.
Conclusions:
- Hybrid human-machine approaches are crucial for the advancement of living systematic reviews.
- These enabling technologies are applicable to both living and standard systematic review methods.
- Further research and development are needed to optimize human-machine integration in evidence synthesis.
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