A new evidence-based risk stratification system for cutaneous squamous cell carcinoma into low, intermediate, and
Christian L Baum1, Adam C Wright2, Juan-Carlos Martinez3
1Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Abstract:
Most primary cutaneous squamous cell carcinomas are cured with surgery. A subset, however, may develop local and nodal metastasis that may eventuate in disease-specific; death. This subset has been variably termed high risk. Herein, we review; an emerging body of data on the risks of these outcomes and propose an evidence-based; risk stratification for low-, intermediate-, and high-risk tumors that takes into; account both tumor and patient characteristics. Finally, we discuss a framework for; management of these tumors on the basis of data, when available, and our; recommendations when data are sparse.
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