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Related Experiment Video

Updated: Feb 22, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
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Meaningful Methods for Increasing Human Papillomavirus Vaccination Rates: An Integrative Literature Review.

Kristin Vollrath, Susan Thul, Jenny Holcombe

    Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners
    |September 19, 2017
    PubMed
    Summary

    Low human papillomavirus (HPV) vaccination rates persist despite vaccine efficacy. Multicomponent interventions show promise for improving HPV knowledge, provider support, and increasing immunization uptake in pediatric care.

    Keywords:
    Adolescentshuman papillomavirus (HPV)immunization hesitancyimmunization uptakeinterventionvaccine

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    Area of Science:

    • Public Health
    • Vaccinology
    • Preventive Medicine

    Background:

    • Human papillomavirus (HPV) is a common sexually transmitted infection linked to several cancers.
    • Despite proven HPV vaccine efficacy, vaccination rates remain low in the United States.
    • Existing research often focuses on vaccine attitudes, with less emphasis on clinician-driven interventions.

    Purpose of the Study:

    • To identify evidence-based interventions for improving HPV vaccine knowledge.
    • To enhance patient-provider conversations regarding HPV vaccination.
    • To increase HPV immunization uptake through effective strategies.

    Main Methods:

    • An integrative review of literature was conducted.
    • The review focused on identifying best practices and interventions.
    • Key strategies examined included provider education, reminder/recall systems, and chart audit/feedback.

    Main Results:

    • Multicomponent interventions demonstrated a synergistic effect on HPV vaccination.
    • These interventions led to increased provider support for the vaccine.
    • Improved patient/parental attitudes and higher immunization rates were observed.

    Conclusions:

    • Multicomponent strategies are effective in boosting HPV vaccination.
    • These interventions enhance provider vaccine advocacy and patient acceptance.
    • Such approaches offer a promising solution to address vaccination disparities in pediatric settings.