Invasive pulmonary aspergillosis and lung adenocarcinoma: Case report

Michael Boyd1, Shishir Ojha1, Jose Goyos1

  • 1Section of Pulmonary, Critical Care, Environmental, and Sleep Medicine, Carilion Clinic, Roanoke, VA, USAVirginia Tech Carilion School of Medicine, Section of Pulmonary, Critical Care, Environmental, and Sleep Medicine, Carilion Clinic, Roanoke, VA, USA.

Thoracic Cancer
|September 19, 2017
PubMed

Insights

This study reports a rare case of invasive pulmonary aspergillosis and adenocarcinoma in a patient with a lung cavity. It highlights the unexplored association between Aspergillus species and lung cancer development and progression.

Area of Science:

  • Pulmonology
  • Mycology
  • Oncology

Background:

  • The lung disease spectrum related to Aspergillus species is variable.
  • The association between Aspergillus species and lung cancer development/progression is largely unexplored.
  • Pulmonary aspergilloma with lung adenocarcinoma is infrequently reported.

Observation:

  • A rare case of invasive pulmonary aspergillosis was observed.
  • The patient presented with fever and a cavitary lung lesion.
  • An accompanying adenocarcinoma finding was noted in the same patient.

Findings:

  • Invasive pulmonary aspergillosis can co-occur with adenocarcinoma of the lung.
  • This case underscores the potential, though rare, link between fungal lung infections and lung cancer.
  • The clinical presentation included fever and a cavitary lung lesion.

Implications:

  • Further research is warranted to explore the Aspergillus-lung cancer association.
  • This case may inform diagnostic and treatment strategies for patients with concurrent fungal infections and lung cancer.
  • Understanding this association could improve patient outcomes in pulmonary medicine and oncology.

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