Technical Note: A simple algorithm to convert EPID gray values into absorbed dose to water without prior knowledge
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Updated: Feb 22, 2026

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
Published on: February 20, 2021
Christine Boutry1, Aurélie Sors1, Jimmy Fontaine2
1Department of Radiotherapy, Oncorad Garonne, 330 Avenue Marcel UNAL, 82000, Montauban, France.
Purpose:
Full integration of EPID-based dosimetry in a global quality control workflow is still complicated. All the actual solutions are based on a relation between image gray-level signal and total linac-delivered dose. In this study, we propose a simple algorithm relying pixel gray-level of EPID image with average linac delivered dose per acquisition frame.
Methods:
Calibration models are constructed for Varian and Elekta linacs including scattering conditions and EPID-arm backscatter-specific corrections. Only simple homogeneous fields are required to establish the EPID dose conversion model for each x-ray beam. Then, the model was evaluated by comparing calculated and converted dose distributions for homogeneous and modulated beams using gamma maps.
Results:
To fit average dose per frame (Dfnorm ) vs pixel gray value (Ngnorm ) of each EPID image, a logarithmic curve Dfnorm=A+B∗lnNgnorm-C, has been chosen where A, B and C are constants depending on beam energy. Gamma comparison (2%, 2 mm, threshold 15%) between converted images and calculated dose distributions for linac control and pretreatment patient fields led to a gamma pass rate higher than 97% for all the analyzed fields.
Conclusions:
Without a prior irradiation settings knowledge except the incident energy beam, we use EPID as a reliable dose to water detector for both homogeneous and modulated beams.
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