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Updated: Feb 22, 2026
07:57
Necropsy-based Wild Fish Health Assessment
Published on: September 11, 2018
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[Three cases of scombroid poisoning]
Y Harmelin1, T Hubiche1, M Pharaon1
1Service de dermatologie-infectiologie, hôpital de Fréjus-Saint-Raphaël, 240, avenue de Saint-Lambert, 83600 Fréjus, France.
Annales De Dermatologie Et De Venereologie
|September 20, 2017
Summary
Scombroid poisoning, a histamine-induced illness from spoiled fish, presents rapidly with skin and gastrointestinal symptoms. Prompt antihistamine treatment leads to quick symptom resolution.
Area of Science:
- Foodborne Illness
- Toxicology
- Dermatology
Background:
- Scombroid poisoning is a common, yet underdiagnosed, foodborne illness caused by histamine in spoiled fish, particularly from the Scombridae family.
- Histamine formation results from bacterial decarboxylation of histidine in fish, exacerbated by heat and sun exposure.
Observation:
- Three cases of scombroid poisoning following tuna consumption presented with malaise, rash, headache, and nausea within 30 minutes.
- Clinical diagnosis was based on symptom onset and presentation, with rapid improvement after antihistamine and corticosteroid treatment.
Findings:
- Scombroid poisoning symptoms include cutaneous reactions (flush, pruritus, urticarial erythema) and gastrointestinal distress (nausea, cramps, vomiting, diarrhea).
- Symptoms appear rapidly after ingestion and typically resolve within hours with appropriate medical intervention.
Implications:
- Early recognition and diagnosis of scombroid poisoning are crucial, despite its commonality.
- Dermatologists should be aware of scombroid poisoning as a differential diagnosis for acute skin reactions after fish consumption.
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