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Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Steroid-induced Glaucoma: An Avoidable Irreversible Blindness.

Sonia Phulke1, Sushmita Kaushik2, Savleen Kaur3

  • 1Senior Resident, Department of Ophthalmology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Journal of Current Glaucoma Practice
|September 20, 2017
PubMed
Summary
This summary is machine-generated.

Unmonitored steroid use, especially eye drops, can lead to steroid-induced glaucoma, a serious condition causing irreversible blindness. Early recognition and management are crucial for preventing vision loss.

Keywords:
Intraocular pressureOcular hypertensionSteroids.Glaucoma

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Steroids are potent anti-inflammatory drugs used for ocular and systemic conditions.
  • Over-the-counter availability of steroid eye drops facilitates unmonitored use, leading to adverse effects.
  • Cataract and glaucoma are significant ocular side effects of steroid administration.

Purpose of the Study:

  • To review the pathophysiology and epidemiology of steroid-induced glaucoma.
  • To highlight the recognition of steroid-induced ocular side effects.
  • To outline the principles for managing steroid-induced glaucoma and prevent vision loss.

Main Methods:

  • Literature review on steroid-induced glaucoma.
  • Analysis of pathophysiology and epidemiology.
  • Discussion of clinical recognition and management strategies.

Main Results:

  • Steroid-induced ocular hypertension, reported in 1950, increases intraocular pressure (IOP).
  • Chronic steroid use with elevated IOP can progress to optic neuropathy, resulting in steroid-induced glaucoma.
  • Self-prescription of steroids poses risks of irreversible blindness.

Conclusions:

  • Clinicians must be aware of the dangers associated with unmonitored steroid use.
  • Monitoring intraocular pressure is essential during steroid therapy to prevent glaucoma.
  • Steroid-induced glaucoma is an avoidable cause of irreversible blindness.