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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Videos

Bilateral Acute Angle Closure Glaucoma Following Phentermine Monotherapy.

Zaid Parekh1, Arjav Shah2, Philip Zhou2

  • 1Pritzker School of Medicine, University of Chicago, Illinois, USA.

Journal of Current Glaucoma Practice
|June 15, 2026
PubMed
Summary

Phentermine monotherapy can cause acute angle closure glaucoma, even after stopping topiramate. This case highlights the importance of assessing ocular risks with weight loss drugs like phentermine.

Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Weight loss medications like topiramate and phentermine carry ocular risks.
  • Topiramate is known to cause acute bilateral angle closure glaucoma.
Keywords:
Adverse effectsAngle closure glaucomaBilateral angle closureCase reportChoroidal effusionDrug-induced acute angle closure glaucomaPhentermineTopiramateWeight loss medications

Related Experiment Videos

  • Phentermine is contraindicated in glaucoma and has limited reported associations with angle closure.