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Retinal Pigment Epithelial Detachment Following Topical Travoprost Therapy
Meghana Narapareddy1, Narayanan Balakrishnan1, Mohamed Anjum Iqbal2
1Department of Ophthalmology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Journal of Current Glaucoma Practice
|August 12, 2026
Summary
Travoprost, a glaucoma medication, may rarely cause retinal pigment epithelial detachment (RPED). Promptly stopping travoprost and switching treatments led to full recovery in three patients, suggesting a reversible drug association.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Glaucoma Management
Background:
- Prostaglandin analogs like travoprost are first-line treatments for lowering intraocular pressure in primary open-angle glaucoma.
- While effective, rare posterior segment complications associated with prostaglandin analogs have been documented.
- Retinal pigment epithelial detachment (RPED) is an uncommon adverse event linked to travoprost use, with limited existing literature.
