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Anesthesia Management of a Child with Osteopetrosis

Hashem Jarineshin1, Fereydoon Fekrat1, Mehdi Feiz Dowlat Abadi1

  • 1Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Anesthesia, Essays and Researches
|September 21, 2017
PubMed

Insights

Anesthesia management for a femur fracture in a child with malignant infantile osteopetrosis is complex. This case highlights considerations for this rare genetic disorder affecting bone development and overall health.

Area of Science:

  • Anesthesiology
  • Pediatric Orthopedics
  • Medical Genetics

Background:

  • Osteopetrosis is a rare genetic bone disorder characterized by osteoclast dysfunction.
  • Malignant infantile osteopetrosis presents with severe skeletal and systemic complications.
  • Femur fractures in affected children require specialized anesthetic approaches.

Observation:

  • A 4-year-old girl with malignant infantile osteopetrosis presented with a femur fracture.
  • The patient had multiple comorbidities including a ventriculoperitoneal shunt, impaired mobility, visual impairment, growth failure, facial deformity, heart murmur with tricuspid regurgitation, left ventricular heart failure, splenomegaly, and severe anemia.

Findings:

  • This case details the anesthesia management strategy for surgical intervention in a pediatric patient with severe osteopetrosis.
  • The anesthetic plan addressed the patient's complex medical history and potential intraoperative risks.

Implications:

  • Effective anesthesia management is crucial for successful surgical outcomes in children with osteopetrosis.
  • This case underscores the importance of multidisciplinary care and tailored anesthetic protocols for rare genetic bone diseases.
  • Further research into anesthetic considerations for osteopetrosis patients is warranted.

Keywords:
Airway managementbone fractureosteopetrosis

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