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Clinical features of 50 cases of 2019 novel coronavirus in Bandar Abbas, Iran

Hashem Jarineshin1, Fateme Saljoughi2, Hamideh Estabraghnia Babaki1

  • 1Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Medical Journal of the Islamic Republic of Iran
|May 17, 2021
PubMed

Insights

This study details the clinical features and outcomes of 50 coronavirus disease 2019 (COVID-19) patients. Key findings include common symptoms, laboratory abnormalities, and risk factors associated with severe illness and mortality in COVID-19.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Critical Care Medicine

Background:

  • Limited data exists on the clinical presentation and outcomes of coronavirus disease 2019 (COVID-19).
  • Understanding COVID-19's impact is crucial for effective patient management and public health strategies.

Purpose of the Study:

  • To describe the epidemiological, demographic, clinical, laboratory, and radiological features of COVID-19 patients.
  • To compare outcomes between critically ill and non-critically ill COVID-19 patients.
  • To identify factors associated with mortality in COVID-19.

Main Methods:

  • A single-center retrospective observational study of 50 COVID-19 patients.
  • Collection and analysis of epidemiological, demographic, clinical, laboratory, radiological, and treatment data.
  • Comparison of outcomes between critically ill and non-critically ill patient groups.

Main Results:

  • The average patient age was 48.8 years, with a male predominance. Common symptoms included dry cough, fever, and dyspnea. Chronic medical illnesses were present in 56% of patients.
  • Frequent laboratory abnormalities included lymphopenia, neutrophilia, thrombocytopenia, elevated liver enzymes, creatinine, lactate dehydrogenase, ESR, and CRP. Chest CT scans often showed bilateral ground-glass opacities and consolidation.
  • 10% of patients died, with mortality higher in men and those with chronic illnesses or requiring invasive mechanical ventilation. Blood oxygen saturation differed between survivors and non-survivors.

Conclusions:

  • COVID-19 presents with a wide spectrum of signs and symptoms.
  • Laboratory findings suggest potential cellular immune deficiency, myocardial, hepatic, and kidney injury associated with COVID-19.
  • Further research is necessary to fully understand the pathogenesis of COVID-19.

Keywords:
COVID-19Chest CT scanClinical featuresCoronavirus disease 2019LaboratoryOutcomesSARS-CoV-2

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