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Occupation and chronic obstructive pulmonary disease in Minsk tractor plant workers
Denis Vinnikov1,2, Sergey Semizhon3, Tatsyana Rybina4
1al-Farabi Kazakh National University, Almaty, Kazakhstan.
Background:
The aim of this study was to measure the association of exposure to dust at workplace with COPD using objective methods of exposure and outcome classification.
Methods:
Forced expiratory volume in one second (FEV1 ) to forced vital capacity (FVC) <70%; FVC below LLN, and FEV1 below LLN from the annual screening of Minsk Tractor Plant workers (N = 458) were tested for predictors in an adjusted logistic regression model.
Results:
In a regression model, adjusted for pack-years of smoking, age, sex, and work duration, work in highly exposed workplaces was associated with FEV1 /FVC<70% (odds ratio (OR) 2.10 (95% confidence interval (CI) 1.16;3.83); and FEV1
Conclusions:
Workers in highly exposed to dust workplaces had double odds of developing COPD.