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Related Experiment Videos

Preliminary validation of the Claudication Symptom Instrument (CSI).

Todd C Edwards1, Danielle C Lavallee1, Alexander W Clowes1

  • 11 University of Washington, Seattle, WA, USA.

Vascular Medicine (London, England)
|September 22, 2017
PubMed
Summary

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The Claudication Symptom Instrument (CSI) was developed to evaluate intermittent claudication (IC) symptoms. This validated tool demonstrates good reliability and sensitivity, aiding in clinical assessment and treatment evaluation for IC patients.

Area of Science:

  • Vascular Medicine
  • Patient-Reported Outcomes
  • Instrument Development

Background:

  • Intermittent claudication (IC) significantly impacts patients' quality of life.
  • Accurate assessment of IC symptoms is crucial for effective treatment and management.
  • Existing instruments may not fully capture the patient's symptom experience.

Purpose of the Study:

  • To develop and validate the Claudication Symptom Instrument (CSI) for assessing IC symptoms.
  • To evaluate the measurement properties of the CSI, including content validity, reliability, and validity.
  • To establish the CSI's utility in clinical practice and research.

Main Methods:

  • Qualitative interviews with IC patients for item generation.
  • Cognitive interviews to test item comprehension.
Keywords:
intermittent claudicationperipheral artery disease (PAD)symptom assessmentvalidation

Related Experiment Videos

  • Rasch analysis and statistical evaluation of measurement properties using observational study data.

    • Main Results:

    • Developed and cognitively tested items for five key symptoms: Pain, Numbness, Heaviness, Cramping, and Tingling.
    • Rasch analysis supported an overall CSI score (χ²=26.5, df=20, p=0.15).
    • Demonstrated good test-retest reliability (ICC=0.86) and sensitivity to change, correlating with VASCUQOL scores (r=-0.52, p<0.05).

    Conclusions:

    • The CSI preliminarily meets accepted standards for content validity, reliability, construct validity, and sensitivity.
    • The CSI is a reliable and valid instrument for evaluating the symptom experience in patients with intermittent claudication.
    • Its high test-retest reliability suggests utility in individual patient clinical care, with a completion time of approximately 3 minutes.