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Related Experiment Videos

Core outcomes in periodontal trials: study protocol for core outcome set development.

Thomas J Lamont1, Jan E Clarkson2, David N J Ricketts2

  • 1Dundee Dental School, Park Place, University of Dundee, Dundee, UK. t.lamont@dundee.ac.uk.

Trials
|September 22, 2017
PubMed
Summary

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This study develops a standardized core outcome set for periodontal disease research. This will improve the quality and comparability of clinical trials and systematic reviews on prevention and management.

Area of Science:

  • Periodontology
  • Clinical Trials
  • Health Outcomes Research

Background:

  • Heterogeneity in clinical outcome measures for periodontal disease hinders data synthesis for systematic reviews and guidelines.
  • A standardized core outcome set is needed to improve the consistency of reporting in periodontal disease trials.
  • This study aims to develop a core outcome set for effectiveness trials in periodontal disease prevention and management.

Framework:

  • Utilizing existing outcomes identified from Cochrane systematic reviews on periodontal disease.
  • Employing a consensus-driven approach involving key stakeholders: patients, dental professionals, researchers, and policymakers.
  • Defining the core outcome set through an online e-Delphi process followed by a face-to-face meeting.

Implementation:

Keywords:
Clinical trialDelphi techniqueDentistryOutcomesPeriodonticsReview

Related Experiment Videos

  • Stakeholders will prioritize outcomes and provide feedback through multiple rounds of the e-Delphi process.
  • Outcomes identified during the Cochrane review screening will be considered by stakeholders.
  • Consensus on outcome inclusion will be determined using predefined rules after the final meeting.

Implications:

  • The developed core outcome set will be relevant to all key stakeholders in periodontology.
  • Findings will be disseminated to enhance clinical trials, systematic reviews, and clinical guidelines.
  • Ultimately aims to improve the prevention and management strategies for periodontal diseases.