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Updated: Feb 22, 2026

05:13
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
756
No. 349-Substance Use in Pregnancy.
Alice Ordean1, Suzanne Wong1, Lisa Graves1
1Toronto, ON.
Summary
This guideline provides evidence-based recommendations for healthcare providers on screening and managing problematic substance use in pregnant women. Early intervention improves maternal and neonatal outcomes and reduces healthcare costs.
Area of Science:
- Obstetrics and Gynecology
- Addiction Medicine
- Maternal-Fetal Medicine
Background:
- Problematic substance use during pregnancy presents significant challenges to maternal and infant health.
- Effective management requires up-to-date, evidence-based guidance for healthcare providers.
Purpose of the Study:
- To enhance healthcare provider knowledge and comfort in managing substance use disorders in pregnant individuals.
- To provide evidence-based recommendations for screening and treatment.
Main Methods:
- Literature review of Medline, PubMed, and Cochrane Library (1996-2016) focusing on pregnancy and substance use.
- Inclusion of systematic reviews, RCTs, controlled trials, and observational studies.
- Quality of evidence and recommendations ranked using Canadian Task Force criteria.
Main Results:
- Presents evidence-based recommendations for screening and management of problematic substance use in pregnancy and lactation.
- Covers screening tools, general care approaches, and specific clinical management strategies.
Conclusions:
- Improved provider knowledge and comfort can lead to better patient care.
- Enhanced access to addiction care reduces maternal and neonatal morbidity and mortality, and lowers healthcare costs.
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