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Methylene Blue for Bronchopleural Fistula Localization.
Kenneth K Sakata1, Faria Nasim, Dante N Schiavo
1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Journal of Bronchology & Interventional Pulmonology
|September 23, 2017
Summary
Diagnosing bronchopleural fistulas (BPF) is difficult. Instilling methylene blue into the pleural space and visualizing it bronchoscopically offers a successful method for BPF localization.
Area of Science:
- Pulmonology
- Thoracic Surgery
Background:
- Bronchopleural fistula (BPF) is a communication between the pleural space and bronchial tree.
- BPFs present diagnostic challenges and are linked to high morbidity and mortality.
- Sequential balloon occlusion is a common diagnostic method for BPFs.
Observation:
- This study details 4 cases of successful bronchopleural fistula localization.
- Methylene blue was instilled into the pleural space via a pigtail catheter.
- Simultaneous bronchoscopic visualization confirmed dye presence in the tracheobronchial tree.
Findings:
- Methylene blue instillation combined with bronchoscopy effectively localized bronchopleural fistulas.
- This technique offers a viable alternative for BPF diagnosis.
Implications:
- Successful localization facilitates timely and appropriate BPF management.
- This method may improve patient outcomes by enabling earlier intervention.
- Further research can explore the broader application of this technique in clinical practice.

