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Updated: Feb 22, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
Published on: December 7, 2012
A novel approach to improving efficiency and cost saving in preoperative blood preparation
Sephalie Y Patel1, David A Edwards2, David C Boulware3
1Department of Anesthesiology, H. Lee Moffitt Cancer Center, Tampa, Florida.
Background:
Preoperative ordering of blood products has been an area of optimization due to considerable variability among physicians; overpreparation can lead to extra costs and underpreparation of blood can potentially compromise patient safety.
Study Design And Methods:
We examined the potential cost savings of extending the storage interval of a presurgical type-and-screen sample from 7 to 14 days, thereby reducing the need for a new specimen on the day of surgery.
Results:
Sensitivity analysis showed annual cost savings for our institution to be an estimated $38,770 ($22,420-$73,120).
Conclusion:
These results are even more robust when incorporating the additional potential savings from improved operating room efficiency.
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