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Updated: Feb 22, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Synthesis of Tetranuclear Palladium(II) Complexes and Their Catalytic Activity for Cross-Coupling Reactions
Florian Puls1, Nils Richter1, Olga Kataeva2
1Department Chemie, Technische Universität Dresden, Bergstrasse 66, 01069, Dresden, Germany.
Abstract:
We have developed a short and simple synthesis of tetranuclear palladium(II) complexes that have been structurally confirmed by X-ray analysis. These complexes were formed in about 30 % overall yield by spontaneous metalation of dimethylaminoarene derivatives and exhibit a high stability. We have studied the utility of the tetranuclear palladium(II) complexes as precatalysts for Mizoroki-Heck and Suzuki-Miyaura cross-coupling reactions. Our novel complexes show excellent catalytic activities with high turnover numbers (TON) and high turnover frequencies (TOF) (e.g., for the Suzuki-Miyaura reaction: TON up to 538000 and TOF up to 23400 h-1 at room temperature).
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